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Integrated DNA
Technologies, BVBA

Provisorium 2
Minderbroedersstraat 17-19
B-3000 Leuven
BELGIUM

Tel: +32-16-337096
Fax: +32-16-337097

info@rna-tec.com





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RNA-tec: Aptamers .

Aptamers

Aptamers are DNA or RNA molecules that have been selected from random pools based on their ability to bind other molecules. Aptamers have been selected which bind nucleic acid, proteins, small organic compounds and even entire organisms. These novel molecules have many potential uses in medicine.


•  Purity: All purities ranging from 90 to 98 % are available. As we have a lot of experience in purifying complex nucleic acids.


•  Yield: The yield depends upon the purity you require and the length of the oligo. See yield example.


•  Typical products: For in vivo experiments we are producing in the range of 10 mg to 50 mg of pure product. Larger quantities are available on request.


•  Modifications: For stabilizing your aptamers we have several modifications available: pyrimidine 2’-fluoro-2’-deoxyribonucleotides (the purine analogues will be available soon) and 2’-O-Me monomers and all other modifications that are commercially available can be incorporated by us.

•  Yield examples: 19 µmol scale of a 40mer including internal linkers and an amino-modifier resulted in a yield of 20 mg of pure product. The chromatograms and more detailed information will soon appear on our website.

RNA-tec: Aptamers .